Advances in Skin, Wound Care and Tissue Science

Wound Healing and Repair

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Wound healing is a specific biological process related to the general phenomenon of growth and tissue regeneration. Wound healing progresses through a series of interdependent and overlapping stages in which a variety of cellular and matrix components act together to reestablish the integrity of damaged tissue and replacement of lost tissue. Wound healing has four continuous phases including haemostasis, inflammation, proliferation and wound remodelling with scar tissue deposition. In an attempt to reduce the wound burden, much effort has focused on understanding the physiology of healing and wound care with an emphasis on new therapeutic approaches and the continuing development of technologies for acute and long term wound management. The clinician working in wound care needs to become a detective. All possible factors and cofactors that may influence healing must be identified. Due to the multifactorial nature of chronic wounds, a thorough health and physical assessment is mandatory.